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Software: HWDIAG

Hardy

Weinberg

DIAGnostics

Version 2.0
Last modified: August 21, 2005, 3:00 PM

André Rogatko
Roy Xu

HWDIAG is a Windows 98/NT program implementing the methods described in the paper "Hardy-Weinberg Equilibrium Diagnostics" by A. Rogatko, M.J. Slifker, and J.S. Babb (Theor. Popul. Biol. 62:251-257). This is the abstract from the paper:
We propose two diagnostics for the statistical assessment of Hardy-Weinberg equilibrium. One diagnostic is the posterior probability of the complement of the smallest highest posterior density credible region that includes points in the parameter space consistent with the hypothesis of equilibrium. The null hypothesis of equilibrium is to be rejected it if this probability is less than a pre-selected critical level. The second diagnostic is the proportion of the parameter space occupied by the highest posterior density credible region associated with the critical level. These Bayesian diagnostics can be interpreted as analogs of the classical type I and II error probabilities. They are broadly applicable: they can be computed for any hypothesis test, using samples of any size generated according to any distribution.


Download HWDIAG 2.0 (Windows Executable)
Download the User Guide (HTML Document)

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